Alex McLeish has confirmed that Darren Bent will play no further part this season, and revealed on Tuesday that James Collins had yet to make a return to training and remains a doubt for the visit of Spurs.
The game between these sides at White Hart lane was possibly Villa's worst performance of the season, though they will most likely adopt a similar approach of playing defensive wide men to act as cover for the full backs against the likes of Bale and Lennon.
Stephen Ireland could come back into the side to add a little more creativity in central midfield, but McLeish will demand work rate, so N'Zogbia could be sacrificed.
Collins, Herd and Delph have all been disciplined for a late night fracas at a nightclub after the annual awards evening and may well be dropped.
Scott Parker remains a doubt for Spurs, but Redknapp is likely to name the same side that have picked up back to back wins against a couple of Villa's relegation rivals this week.
Therefore, the likes of Sandro and Rose will keep their places, with Assou-Ekotto likely to miss the rest of the season, while Walker and Friedel will return to Villa Park for the first time since leaving the club last summer.
Ledley King and Ryan Nelsen are both alternative options at the back, but Gallas and Kaboul should continue in the heart of the defence.
It has been revealed that Kyle Walker has a broken toe but due to the lack of options will play having had injections in the week.
This is another huge game for both sides, with the potential impact that this result could have at either end of the table. If Villa picked up an unexpected result they would be all but safe, where a win for Tottenham will mean that they could still go down in the last gameweek.
If the visitors were to win, and they will be favourites to do so, then they will remain in the driving seat to finish at least 4th and keep the pressure up on Arsenal in 3rd going into the last day of the season.
Games between these two sides at Villa Park have been extremely close in recent years, with both sides scoring in the last 6 encounters in the Midlands, though Villa have won just once in that run.
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