The Netherlands must win, so Bert van Marvijk is likely to throw caution to the wind and drop either van Bommel or de Jong from the midfield, with van der Vaart in line for his first start in the tournament.
The coach may also try and accommodate for another striker, which could see van Persie forced wide and Afellay drop to the bench.
Jetro Willems looked a little out of his depth against Germany and will need to improve as he is likely to be up against an in-form Nani this weekend.
Despite losing their first two matches, Holland can still qualify if they beat Portugal by a 2-goal margin or more, therefore they are likely to go all out for the win with an attacking line-up.
Portugal will look to unsettle youngster Willems on their route to goal as Germany managed, so Nani could be key once again for Bento's side.
Portugal will, however, be focused on a far more solid defensive display, knowing that if Germany beat Denmark as expected a draw, or even a defeat by a 1-goal margin, will see them progress.
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