Ajax have been extremely poor since the turn of the year - they have lost 3 of their 5 games since the winter break and only picked up their first win with a morale-boosting result at NAC Breda at the weekend. They are way down in 6th place in the Eredivisie and look somewhat out of sorts.
They have a fair few injuries in their ranks to contend with.
Boilesen will play at left back, with Anita likely to fill in for the injured Janssen in defensive midfield.
Enoh is out with a hamstring injury, while Van der Wiel is also still out.
With no FA Cup tie to contend with at the weekend, Sir Alex Ferguson will field a strong side for the trip to Ajax.
Cleverley, Jones, Nani and Smalling are all back.
Evra, Berbatov and Giggs have all not travelled with the squad.
It is always difficult to predict the team Ferguson will select. He usually prefers to play Park in European ties, while Ashley Young could be given some much needed game time in his quest regain his early season form, while Carrick has been a regular of late.
However, Scholes, Valencia and Nani could also all be available to play, and will give the manager food for thought.
Meanwhile, up front, Rooney will probably play, though his partner could Hernandez or Welbeck.
Two of European football's heavyweights go head to head in what is thought by many as the tie of the round. It is a sign of changing times that this is being played in the Europa League last 32, seeing as both sides have won the Champions League in the last 20 years. There is no doubting that both sides will be taking this side extremely seriously, though, and there will be no signs of complacency given the manor in which they both bowed out of the Champions League.
Ajax's form has been terrible in recent weeks and they will need to be much improved to get a result here. Sir Alex Ferguson has bags full of European experience, and that, compounded with United's unexpected exit from the Champions League will easily be enough to convince Ferguson that they cannot afford to underestimate their opposition.
United will take the game extremely seriously. They will not want the embarrassment of a Europa League exit and should be strong enough to get the necessary result here, no matter how much history there is between the teams.
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