Alexandre Alphonse is unavailable due to an achilles problem.
Ousmane Coulibaly is out with a groin injury.
Kamel Chafni also looks set to miss out with a knee problem.
Lille will hope to bounce back from their Champions League exit when they welcome Brest to the Grand Stade Metropole.
The 2011 champions enjoyed a comfortable win over Evian last weekend, but surrendered meekly against Bayern Munich in midweek as they were thumped 6-1.
Meanwhile Brest tasted victory in the Breton derby with Lorient. Eden Ben Basat and Charlison Benschop scoring in a 2-0 victory.
However, a trip to Lille is a different proposition, and although Les Dogues have struggled in Europe, the likes of Nolan Roux and Dimitri Payet are beginning to find form in the league, and they should be expected to triumph against a team that finds life more difficult on their travels.
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