Spaniards Rangel and Hernandez both remain doubtful, though Taylor is the only certain absentee.
Agustien was handed a rare start at the weekend and will vie for a place in the side once again with Ki Sung-Yeung and Leon Britton.
Michu may keep his place as the central striker, with either De Guzman or Routledge likely to play the free role if the league's top scorer is fielded up front.
Reading earned a draw at the Liberty earlier in the season and know that they can compete with a free-flowing Swansea side so will be even more confident at home.
Both sides have reason to be in high spirits after impressive displays against the two Manchester clubs at the weekend, though McDermott's side may have had the wind taken out of them by City's injury time winner.
Despite a run of 7 consecutive defeats the Royals have only lost to Tottenham, United and Arsenal at home this season, so this is likely to be a close game.
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