| Player | Reason | Status | Rating |
|---|---|---|---|
| Chris | Out | N/A | |
| Jannik Vestergaard | Out | 6.8 | |
| Stefan Thesker | Out | 6.5 | |
| Boris Vukcevic | Out | 6.89 |
| Player | Reason | Status | Rating |
|---|---|---|---|
| Michal Kadlec | Out | 7.36 | |
| Sidney Sam | Out | 6.9 | |
| Karim Bellarabi | Out | 6.7 | |
| Daniel Schwaab | Out | 6.53 |
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| Bayer Leverkusen will score as a result of individual skill |   |
| Bayer Leverkusen will score from a setpiece situation |   |
| Hoffenheim will make a comeback if they go behind |   |
| Bayer Leverkusen will steal the ball from the opposition often |   |