Mats Hummels returns to replace Felipe Santana at centre-back.
Sebastian Kehl is injured and will be replaced by the more attack-minded Ilkay Gündogan.
Mario Götze will probably return to the starting line-up with Kevin Großkreutz dropping to the bench.
Bayern have had a great season so far and they are already "autumn champions" in record time with an 11-point advantage over Dortmund who are down in third place.
Dortmund could only manage a draw against Düsseldorf during the week; a disappointing result after three wins in a row before that. They have recovered from their poor start to the season but a win in this game is a must if they are to retain any chance of defending their title for a third time.
Expect this to be an intense game with the two main rivals for the title in the last two years trying to get the best of one another.
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