New signing David Abraham will most likely make his debut at centre-back, with Jannik Vestergaard dropping to the bench.
Danny Williams could replace the injured Sejad Salihovic in central midfield.
Joselu has a good chance of starting instead of Eren Derdiyok this time.
Frankfurt lost against Leverkusen last weekend. They need a result at home now to solidify their spot in the European places.
Hoffenheim picked up a promising draw against Gladbach in manager Kurz's first game in charge last weekend. Several new signings this week will strengthen the squad in the long term, but it remains to be seen who can help them leave the relegation zone immediately.
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