Sead Kolasinac will replace Christian Fuchs at left-back again.
Should Roman Neustädter not return from a flu in time, Marco Höger will switch to defensive midfield, with Benedikt Höwedes filling in at right-back and Christoph Metzelder starting in the centre of defence.
Raffael is the first attacking option on the bench.
Wolfsburg have only collected one point from their last two games, but they did well in both of them and seem to have found enough stability to make the next step soon.
After four games without a win, Schalke overcame Düsseldorf at home last weekend. The team needs to continue to improve and help target man Klaas-Jan Huntelaar to find form again.
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