Espanyol picked up a vital win last weekend as they beat Celta Vigo 1-0 to move out of the relegation zone.
Christian Stuani set up Sergio Garcia for the only goal of that game but the Uruguayan is a doubt for the clash with Depor due to a quad injury.
Javier Aguirre will make at least one change though as Hector Moreno returns from suspension, but Kiko Casilla is expected to retain his place in the side despite Cristian Alvarez returning from injury.
Mallorca, however, went in the other direction last weekend as a 3-1 defeat to Valladolid saw them drop into the bottom three.
Moreover, with certain media sources claiming there are those in power at the club considering Joaquin Caparros' position this could be the former Sevilla manager's last chance to save his job.
Kevin Garcia is expected to be handed a rare start at left-back as Pedro Bigas is suspended, but Javi Marquez should be fit to return in midfield
Espanyol have got the upturn in form that they needed since Aguirre's arrival with just one defeat in six and they will be confident of maintaining that momentum on Friday night.
Scoring goals remains the problem for both sides so don't expect a high-scoring encounter but Los Pericos are playing with far greater belief and determination at the moment and should edge it by the odd goal.
WhoScored.com provides you with unparalleled football statistics, as
well as detailed football previews and football rankings from competitions all over the
world. Our live, in-depth football statistics from the Premier League,
supplies unique and original insights for football fans, sports
betting punters, journalists, football managers and players. We also have football tables,
live scores, top performing players as calculated with our unique WhoScored.com
ratings, blogs, graphics, rankings and much more.