Mallorca managed to sign Andreu Fontas on an emergency loan from Barcelona over the international break and he seems set to go straight into the side with Joaquin Caparros' squad beset by injury and suspension.
Ximo Navarro also returns from his ban to start at right-back, with Fontas set to partner Tomas Pina in midfield.
Tomer Hemed continued his amazing scoring form by firing five for Israel in two games over the past week and he will again be the main threat for the Islanders going forward.
Both sides have come back down to earth after sterling starts to the campaign with each having lost their last two matches.
However, with Sevilla back on home soil it would appear as if Mallorca are more likely to continue that poor run.
The absences of Medel and Trochowski will hurt the hosts but similarly Mallorca are without a key trio in Emilio Nsue, Javi Marquez and Joao Victor, and the defensive stability that was so evident in Caparros' side early in the season has dissipated in their absence.
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