Valencia meanwhile will take to the field for the first time on league duty under Ernesto Valverde after he replaced the sacked Mauricio Pellegrino earlier in the week.
Jonas scored the only goal as Valverde got off to a winning start at Lille in the Champions League on Wednesday night, but the Brazilian is suspended for the trip to Pamplona after being sent-off in the 5-2 thrashing against Real Sociedad that ultimately cost Pellegrino his job last weekend.
However, Roberto Soldado, Ever Banega, Fernando Gago and Diego Alves should all return after being rested from the start in midweek.
Osasuna's great run of form has been down to their defensive solidity as they have kept five consecutive clean sheets in all competitions and they will certainly provide a stiff test for a Valencia side that has struggled badly on the road this season.
Valverde is a shrewd operator, though, and should be able to get the best out of what is still a highly talented squad.
Last season's meeting between these two at El Sadar finished 1-1 and it wouldn't be a surprise to see a repeat of that scoreline on Saturday night.
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