Espanyol got off the mark in Javier Aguirre's first match in charge with a 0-0 draw at Granada, but they need to start picking up wins if they are to get off the foot of the table. They have a decent chance here against a Sevilla side whose league form of late hasn't been great.
Sergio Garcia serves the third of his four-game suspension, but Hector Moreno should return as his ban is now up.
Otherwise Christian Stuani is the only doubt for the Catalans so Samuele Longo could regain his place as the lone striker.
Sevilla, meanwhile, suffered their fourth defeat in six league games as a depleted side went down 2-1 to Valladolid on Monday night.
Emir Spahic, Federico Fazio and Ivan Rakitic all return from suspension, but Antonio Luna is still banned and so is Gary Medel after he was sent-off for the second time this season in the Valladolid game.
Alvaro Negredo also remains on the sidelines through injury so Baba Diawara will continue up front.
Hedwiges Maduro and Manu del Moral are both doubtful.
These two met in the Copa del Rey recently with Sevilla comprehensively winning the tie 6-1 but that occurred during the height of Espanyol's institutional crisis, immediately after controversial presidential elections and the sacking of Mauricio Pochettino.
However, even in a more settled environment they are still lacking in goals and Sevilla will be boosted by the return of the influential trio of Spahic, Fazio and Rakitic.
Their last league meeting finished 1-1 at the Cornella towards the end of last season and it is easy to see a repeat of that scoreline come Friday night.
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