Conti is back after his suspension, so one of Ekdal and Dessena will have to sit on the bench.
Pulga will perform an overhaul in defence as Astori and Pisano are suspended, while Murru is favoured over Avelar.
Nenè will partner Sau up front due to Pinilla's injury.
Prediction
Lazio took second place in the final round of fixtures in 2012 from Inter and are undefeated in their last 11 competitive matches. Petkovic's team is in good shape and the coach has almost his entire squad available.
With five consecutive defeats in the league, Cagliari have dropped places and now the relegation zone is just one point below them. Club owner Cellino is growing impatient, but he's keeping his manager for the moment.
Expect the Biancocelesti to retain ball possession and slowly try to make Cagliari get out of their half and leave room for some attacks. The Sardinians will probably defend tight waiting for a chance to counter-attack. Ibarbo would be a useful player in the second half to do so.