Benfica have a full squad to choose from for the trip to Camp Nou, with centre back Luisao back in the fold after serving a 2 month suspension for pushing over a referee. He has played more or less every game since returning and will partner Ezequiel Garay here.
Oscar Cardozo will lead the line with Lima.
Ola John provides another option on the left in place of Gaitan, who has only started twice in the Champions League this season.
Barcelona have nothing riding on this game, with their passage to the next round already secured, but Benfica have everything to play for. The Portuguese side are seond in the group ahead of Celtic, and thus need to match or better the Scottish side's result against Spartak Moscow.
While a trip to Barcelona is hardly the ideal game for Benfica to pick up such a result, the Catalans have looked beatable at home in the Champions League this season, coming from behind after early scares in both if their home games so far - against Celtic and Spartak.
Furthermore, there is no pressure on them to win this time around, other than the fact that the fans might be unhappy with anything but victory. Benfica stand an outside chance of pulling off an upset, but with Messi seeking to make tonight an historic one on a personal level, he may be in unstoppable form.
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