Brendan Rodgers is likely to make wholesale changes to the side that beat Norwich, despite facing a tough opponent in Udinese on Thursday.
The likes of Sahin and Suso were both withdrawn in the second half at the weekend and could start in Europe once again, with Jonjo Shelvey available, with his suspension only ruling him out of domestic competition.
Fabio Borini could get another chance to ignite his Liverpool career in his more favoured central position, while the likes of Henderson, Carragher, Coates and Downing should also be given a chance to impress.
Forward Luis Muriel is injured and will continue to miss out while centre-back Domizzi also missed the game with Genoa at the weekend and Coda should keep his place in the back-three.
Antonio Di Natale and Dusan Basta were both rested at the weekend which suggests that they should start at Anfield despite Guidolin resting numerous players in their opening Europa League tie with Anzhi.
The coach may well name a full-strength side, with the likes of Fabbrini and Faraoni dropping to the bench.
Liverpool will be in confident mood after a comprehensive win at the weekend but will make a lot of changes to the side that beat Norwich, so consistency could be an issue.
Udinese had a poor start to the season but have improved slightly, going unbeaten in their last 5 matches, though goals have proven hard to come by, particularly when Di Natale has been out of the side.
The veteran striker will need to start if Udinese are to get back to winning ways and if the visitors have a chance of scoring goals it may be in this game as Liverpool reshuffle their pack in what is likely to be an open and entertaining match.
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