Liverpool are likely to recall a number of first name stars for this key clash as they are currently level on points with their Swiss opponents, so the likes of Gerrard and Suarez should both start.
Lucas Leiva is nearing a comeback but won't be rushed back to action, though Jonjo Shelvey could be back in contention come Thursday.
Youngsters Sterling and Suso may both be rested, along with the in form Jose Enrique.
Josh Simpson, Josef Martinez and Ivan Benito remain long term doubts, though Christoph Spycher and Jan Lecjaks could be back available.
Dusan Veskovac has been favoured over Finnish centre back Juhani Ojala of late and should keep his place alongside Alain Nef.
Mario Raimondi is suspended having picked up three yellow cards in the competition, while Costanzo and Veskovac are one booking away from a ban
Prediction
This is likely to be one of the most intriguing encounters of the round, with the standings in group A incredibly close, with bottom club Udinese just three points off group leaders Anzhi.
Liverpool know that a win here will see them finish above Young Boys no matter what happens in the final round of fixtures to put them in a great position to qualify from the group, with anything less meaning that they will need some sort of a result in Udine.
A draw would not really be a great result for either side, so both will be out to win this one which should lead to a glut of goals as in the reverse fixture, when the Reds ran out 3-5 winners in Switzerland.
