Steve Von Bergen was substituted off early in the 5-2 defeat to France and could miss out here, with Philippe Senderos expected to partner Johan Djourou in his absence.
Blerim Dzemaili came on at half time and netted late on and could be rewarded with a start.
Haris Seferovic was handed a start on the back of his match winning strike against Ecuador, but may drop the bench here.
Honduras' World Cup campaign came to an end late on Friday with the 2-1 defeat to Ecuador. The Central American nation looked out of depth in Brazil and were never expected to make it out of their group.
Switzerland on the other hand are tipped to progress from Group E. Despite a 5-2 defeat to France, the Swiss still have the quality to make it to the second-round.
The likes of Josip Drmic, Xherdan Shaqiri and Ricardo Rodriguez have the quality to punish Honduras in this one.
Despite looking defensively suspect, Switzerland have the ability to win here.
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