Javier Manquillo is Diego Simeone's only injury concern ahead of the trip to Barcelona.
Atlético will have been buoyed by their win over Athletic at the weekend that took them to the top of La Liga.
Raúl García is suspended, while Emiliano Insua is one booking away from a ban.
Barcelona secured a late 1-0 win over Espanyol on Saturday to remain within a point of league leaders Atlético. While the Blaugrana secured victory, they still struggled to overcome their neighbours and will face a much sterner test on Tuesday.
Atlético sit atop La Liga and will surely be dreaming of securing the title this term. However, they have failed to win any of their last 6 meetings with Barcelona in all competitions, losing 3.
Injury to Valdés has seen Barça's defensive stability drop, though they are still potent going forward. The last 2 fixtures between these two sides have ended 0-0 and a similar result is expected.
WhoScored.com provides you with unparalleled football statistics, as
well as detailed football previews and football rankings from competitions all over the
world. Our live, in-depth football statistics from the Premier League,
supplies unique and original insights for football fans, sports
betting punters, journalists, football managers and players. We also have football tables,
live scores, top performing players as calculated with our unique WhoScored.com
ratings, articles, graphics, rankings and much more.