Juventus manager Massimiliano Allegri made changes to his usual XI at the weekend and is expected to recall upon the services of Leonardo Bonucci, Giorgio Chiellini, Mario Mandžukić and Miralem Pjanic when they host Barcelona on Tuesday night.
Dani Alves will face off against his former club for the first time since leaving Barcelona to join Juventus last summer. Marko Pjaca is the only player unavailable for Juventus.
Juan Cuadrado is a booking away from a ban from the reverse leg.
Sergio Busquets is suspended for the first leg after reaching the yellow card limit in the last round against Paris Saint-Germain. Neymar, Ivan Rakitić and Gerard Piqué are also a booking away from a suspension.
Pique and Rakitic served domestic bans at the weekend and will be fresh to return to the team when they travel to Juventus for the first leg of their Champions League quarter-final tie.
Aleix Vidal and Rafinha are out for the remainder of the season and leave Barcelona limited for choices on the right hand side. Arda Turan missed out at the weekend because of injury and remains a doubt here.
With Busquets sidelined, it remains to be seen how Luis Enrique will line his side up against Juventus and who will fill Busquet's role.
Juventus have never suffered defeat at home to Barcelona and are currently 21 games unbeaten in European home matches, last losing at the Juventus Stadium to Bayern Munich in April 2013.
Barcelona are in the Champions Leaguer quarter-finals for a record 10th season in a row. However, they have only won four their last 10 away matches in the competition and have lost two of their last three.
Luis Enrique's side should be confident of overcoming Juventus over the two legs having triumphed in eight of their 11 two-legged matches against Italian sides. Juventus should be favoured here, however.
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