Adam Lallana stepped up his return to fitness with the U23s in the week and while he was sent off in that game, he won't face a ban here.
Jurgen Klopp has confirmed Joe Gomez will not feature here, joining Nathaniel Clyne on the sidelines. Ragnar Klavan has trained, however.
Trent Alexander-Arnold will continue at right-back, while Georginio Wijnaldum may feature in midfield at James Milner's expense.
Southampton secured a morale boosting 3-2 win over West Brom last weekend to end a 12-match winless run and open up a two-point gap between themselves and the relegation zone. They haven't won a home Premier League match since November, however, and the welcome of Liverpool will pose a tougher test than table footers West Brom.
Liverpool were twice pegged back by Tottenham on Sunday to settle for a 2-2 draw. The Reds have lost just one of their last 17 Premier League matches, that coming in a recent 1-0 defeat at Swansea and the trip to Southampton will be tough to navigate, even with the home side's poor form at St. Mary's.
That being said, the Reds have what it takes to land another three points in what promises to be an entertaining affair on the south coast.
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