Benjamin Stambouli challenges Thilo Kehrer for his spot in the back-three.
Leon Goretzka has recovered from injury and could get another chance in the starting XI.
Marko Pjaca is expected to start alongside Guido Burgstaller again.
Stuttgart have lost five of their last six league games and sit only four points above the relegation play-off spot. Their only two home defeats this season came to Leverkusen and Bayern and they will face another strong team at the Mercedes-Benz-Arena here.
Schalke have struggled recently, winning only one of their last seven matches. They have to be more creative in midfield again to break down a more defensive-minded Stuttgart side.
Expect this to be an intense game from the outset.
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