Luciano Spalletti has a full squad to pick from on the last day of the season.
Roberto Gagliardini has only just returned from injury and may not be fully fit to start.
Lazio will be left kicking themselves if they miss out on a place in the top four this season. They have drawn their last two matches and a defeat here on the final day of the season would hand Inter fourth place due to a superior head-to-head advantage.
Inter missed the chance to draw level on points with Lazio last weekend after slipping to a shock defeat to Sassuolo. Now it means they have to win in order to finish fourth and secure the final Champions League position.
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