Toby Alderweireld has been left in London to build up his fitness and misses out for Tottenham.
Other than that, Mauricio Pochettino has the luxury of a fully fit squad to choose from here.
The Spurs boss may bring Serge Aurier in for Kieran Trippier at right-back, while Victor Wanyama could replace Heung-min Son should Pochettino look to keep things tight early on.
Juventus extended their fine run of form with a solid 2-0 win at Fiorentina on Friday night and are brimming with confidence as they welcome Tottenham to Turin. The Italian side have conceded just one goal in their last 16 matches, though Tottenham will look to break their defensive resolve.
Spurs secured a morale boosting 1-0 win over north London rivals Arsenal in Saturday's early kick off, though their away form leaves little to the imagination. They've failed to win in three on the road and have won only two of their last eight matches away from home.
A single goal could decide this one and considering their solid defence, Juventus may edge the first leg.
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