- Manchester United right-back Aaron Wan-Bissaka has withdrawn from the squad with a back injury, though no replacement has been called up. With Kyle Walker not in the squad, Kieran Trippier or Trent Alexander-Arnold will start here.
- Mason Mount, James Maddison and Tyrone Mings will hope to make their senior England debuts but have more chance of starting in next week's qualifier against Kosovo.
- Marcus Rashford is expected to be the forward to miss out on a start, with Raheem Sterling, Harry Kane and Jadon Sancho preferred.
- Bulgaria played a variety of formations during their UEFA Nations League campaign but are expected to line up defensively on Saturday.
- Todor Nedelev, Georgi Kostadinov and Bozhidar Chorbadzhiyski were regulars for Bulgaria during the UEFA Nations League but none are available for the away side for this international break.