Jose Enrique is set to be out for a few weeks with a hamstring injury, so Andre Wisdom will play at right-back again with Glen Johnson on the left.
In recent weeks Joe Allen has started on the bench with Jordan Henderson preferred. Given that Liverpool have won their last 2 league games 3-0, they will probably stick with those players.
Daniel Sturridge made a goalscoring start to life at Liverpool and could be in line for his first Premier League game for his new club, though he may only appear from the bench, where he may be joined by a fit again Fabio Borini.
One of the most feisty and fiercely contested games in Premier League history, this fixture has seen 14 red cards over the years, and a great deal of drama to boot. Despite United's greater success in recent years, results have been fairly balanced between the teams.
The last 5 fixtures in all competitions have seen 2 wins apiece and a draw, though generally the home team has dominated. With United top of the table and 7 points clear, they will go all out for the win and will dominate on home soil.
The Red Devils have won 8 of their last 9 league games, and while Liverpool have won 5 of their last 7 to move up to 8th in the table, United are in unstoppable form and should be victorious. The fans will be fired up for the derby and that could will add to the hostile atmosphere. We should see a fair few cards and a portion of drama as well.
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