Paolucci may start on the bench this time as Reginaldo and Bogdani are favoured to play up front.
Rubin and Del Grosso are in competition to play on the left flank.
The defence will be the usual trio of Neto, Contini and Felipe.
Udinese ended their six-match unbeaten streak by losing heavily to Juventus last time around, but at home they haven't suffered defeat in their last nine matches (the last home defeat was against Juventus).
Siena have only collected 5 points in 10 matches away from the Franchi, but their last victory against Sampdoria put an end to a losing streak that lasted for seven matches (includine one in Coppa Italia) and gave them back some hope to reach safety.
The hosts will want to make up for the 4-0 loss suffered in Turin and will push from the start, forcing Siena to fall back and defend tight. Udinese's pressure should be enough to ensure a lead in the first half, especially as Di Natale will be leading the attack once again.
WhoScored.com provides you with unparalleled football statistics, as well as detailed football previews and football rankings from competitions all over the world. Our live, in-depth football statistics from the Premier League, La Liga, Serie A, Bundesliga, Ligue 1, Eredivisie, Russian Premier League, Brasileirão, MLS, Super Lig and Championship supplies unique and original insights for football fans, sports betting punters, journalists, football managers and players. We also have football tables, live scores, top performing players as calculated with our unique WhoScored.com ratings, articles, graphics, rankings and much more.