David Silva was withdrawn from the Spain squad for the friendly against Chile on Tuesday and remains a doubt for the trip to Stoke with a thigh injury.
Vincent Kompany, Micah Richards and newly-signed Martin Demichelis are all out, meaning City are still looking rather short at the back.
If Silva doesn't make it back in time, Samir Nasri will be on standby to play.
Having won their last two matches, Stoke will be looking to win 3 consecutive matches for the first time since November/December last year, but up against Manchester City they face a tough task.
Each of the last 4 Premier League meetings between the sides at the Britannia have ended in a 1-1 scoreline, and if Mark Hughes was to answer honestly, he'd probably admit he'd be happy with a repeat scoreline this time around.
Manuel Pellegrini, meanwhile, after losing at Cardiff, will be after a first away win at Manchester City. Another 1-1 could just be on the cards, though.
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