Ecuador showed their potential with an impressive performance in their recent 2-2 draw with England in Miami.
Antonio Valencia was red-carded in the stalemate, but will be available for their Group E opener with the Swiss.
Enner Valencia headed in the opener in the draw and should start in attack alongside Felipe Caicedo.
Switzerland breezed through their qualifying group to make the World Cup, taking 24 points from a possible 30 and their young, exciting squad should attract interest from neutrals this summer.
The Swiss conceded just 6 goals in qualifying, so they are a tough team to break down. They'll be confident of continuing these resolute defensive performances in Brazil, but will be put to the test against Ecuador in their Group E opener.
Ecuador scraped into the competition without the need for a playoff due to their better goal difference than Uruguay and their recent display against England recently will have boosted morale in the squad.
However, away from the Estadio Olímpico Atahualpa, the South American outfit struggled, though they could fair better in the humid conditions in Brazil than their European counterparts.
Both teams are fairly evenly matched, but Switzerland's quality could seen them scrape a win.
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